منابع مشابه
Is bigger better?
What is medical science all about? Surely it is about the value chain, which begins with basic research and ends—if there is an end— with a useful product. There is a widespread perception that scientists do a lot of basic research, but neglect the application of their findings. To remedy this, a number of organizations and philanthropists have become dedicated advocates of applied or translati...
متن کاملSometimes, more is better.
(See the article by El Sahly et al, on pages 703–12.) Influenza causes significant morbidity and mortality with an estimated 36 000 attributable deaths in the United States annually [1]. Human immunodefi-ciency virus (HIV) infection, specifically , advanced disease (CD4 count ,200 cells/lL), has been associated with excess morbidity and mortality [2]. With the use of combination antiretroviral ...
متن کاملIs Bigger Better? Investing in Reputation
We develop a model in which the value of a firm’s reputation for quality increases gradually over time. In our model, a firm’s ability to deliver high quality at any given period depends on how much it invests in quality. This investment is the firm’s private information. Also, a firm’s current quality is unobservable. Thus the only observable is a firm’s past performance the realized quality o...
متن کاملCommentary YAC transgenes : Bigger is probably better
A number of recent articles have reported the successful generation of transgenic mouse lines carrying large fragments of DNA contained in yeast artificial chromosomes (YACs) (1-5). The ability to transfer such large segments of DNA provides a number of opportunities, including the analysis ofthe function of large genes or gene clusters in their natural DNA configuration, the study of the influ...
متن کامل802.11 Buffers: When Bigger Is Not Better?
While there have been considerable advances in the modelling of 802.11’s MAC layer in recent years, 802.11 with finite buffer space is considered difficult to analyse. In this paper, we study the impact of finite buffers’ effect on the 802.11 performance, in view of the requirements of interactive applications sensitive to delay and packet loss. Using both state-of-the art and simplified queuei...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2002
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jcem.87.1.8266